Alzheimer’s disease (AD) is a physical disease that affects the brain. It is named after Alois Alzheimer, the doctor who first described it in 1906.
AD is a chronic neurodegenerative (loss of brain cells) disease that usually starts slowly and gradually worsens over time.
With current treatments for AD only providing temporary symptomatic benefits, disease modifying drugs are urgently required. This approach relies on improved understanding of the early pathophysiology of AD.
In this short online lecture, Dr Michael Harte from the Division of Pharmacy & Optometry, University of Manchester will give an overview of what goes wrong in the brain in AD and highlight the difficulties in developing new treatments.